Yuto Yamazaki Selected Research

Cytochrome P-450 CYP11B2 (CYP11B2)

1/2022	Phenotype-genotype correlation in aldosterone-producing adenomas characterized by intracellular cholesterol metabolism.
1/2022	Characteristics of aldosterone-producing adenomas in patients without plasma renin activity suppression.
2/2021	Primary aldosteronism due to bilateral micronodular hyperplasia and concomitant subclinical Cushing's syndrome: A case report.
1/2021	Pathology of Aldosterone Biosynthesis and its Action.
9/2020	A case of Williams syndrome with suspected coexisting ectopic aldosterone-producing tumor in the liver.
1/2020	Histological Characterization of Aldosterone-producing Adrenocortical Adenomas with Different Somatic Mutations.
10/2019	The crosstalk between aldosterone and calcium metabolism in primary aldosteronism: A possible calcium metabolism-associated aberrant "neoplastic" steroidogenesis in adrenals.
10/2018	Cellular and Genetic Causes of Idiopathic Hyperaldosteronism.
1/2018	Tumor Cell Subtypes Based on the Intracellular Hormonal Activity in KCNJ5-Mutated Aldosterone-Producing Adenoma.
11/2017	Evaluation of Cortisol Production in Aldosterone-Producing Adenoma.

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Yuto Yamazaki Research Topics

Disease

32	Neoplasms (Cancer) 01/2022 - 06/2015
30	Adenoma (Adenomas) 02/2022 - 01/2016
26	Hyperaldosteronism (Conn Syndrome) 01/2022 - 09/2015
12	Hyperplasia 09/2021 - 01/2017
11	Hypertension (High Blood Pressure) 01/2022 - 09/2015
11	Adrenocortical Adenoma (Disease, Conn's) 07/2021 - 01/2016
9	Cushing Syndrome 07/2021 - 01/2016
5	Adrenocortical Carcinoma 01/2022 - 06/2015
5	Pheochromocytoma 10/2021 - 10/2016
4	Neuroendocrine Tumors (Neuroendocrine Tumor) 12/2021 - 10/2016
2	Carcinoma (Carcinomatosis) 11/2021 - 01/2017
2	Hemorrhage 01/2021 - 10/2016
2	Disease Progression 01/2021 - 08/2019
2	Cardiovascular Diseases (Cardiovascular Disease) 06/2020 - 01/2018
2	Osteoporosis 06/2020 - 10/2019
2	Paraganglioma (Paragangliomas) 05/2020 - 01/2020
2	Diabetes Mellitus 01/2020 - 09/2017
2	Virilism (Virilization) 01/2020 - 01/2017
1	Biliary Atresia 06/2022
1	Breast Ductal Carcinoma 06/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 06/2022
1	Ductal Carcinoma 06/2022
1	Tuberous Sclerosis (Bourneville's Disease) 09/2021
1	Lymphangioleiomyomatosis (Lymphangiomyomatosis) 09/2021
1	Thrombosis (Thrombus) 07/2021
1	Small Cell Carcinoma 02/2021
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 02/2021
1	Lung Diseases (Lung Disease) 01/2021
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021
1	Dysgerminoma 01/2021
1	Precocious Puberty 01/2021
1	Ulcerative Colitis 01/2021
1	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 01/2021
1	Williams Syndrome (Williams-Beuren Syndrome) 09/2020
1	Hypokalemia 09/2020
1	Hypocalcemia 06/2020
1	Hypercalciuria 06/2020
1	Metabolic Diseases (Metabolic Disease) 06/2020
1	Hypogonadism (Hypergonadotropic Hypogonadism) 02/2020
1	Leiomyoma (Uterine Fibroids) 01/2020

Drug/Important Bio-Agent (IBA)

35	AldosteroneIBA 01/2022 - 09/2015
19	Hydrocortisone (Cortisol)FDA LinkGeneric 02/2022 - 01/2016
17	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 01/2022 - 01/2016
10	SteroidsIBA 01/2022 - 06/2015
9	Adrenocorticotropic Hormone (ACTH)FDA Link 10/2021 - 01/2017
7	EnzymesIBA 01/2022 - 01/2016
7	Hormones (Hormone)IBA 11/2020 - 01/2017
5	Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)IBA 01/2022 - 01/2016
5	ReninIBA 01/2022 - 01/2017
5	Biological ProductsIBA 02/2021 - 06/2015
4	AndrogensIBA 11/2021 - 01/2017
4	CatecholaminesIBA 10/2021 - 10/2016
3	Estrogens (Estrogen)FDA Link 01/2021 - 01/2017
2	DNA (Deoxyribonucleic Acid)IBA 06/2022 - 12/2020
2	CholesterolIBA 02/2022 - 01/2022
2	Messenger RNA (mRNA)IBA 01/2022 - 10/2019
2	nasIBA 01/2022 - 10/2019
2	4- (4- dihexadecylaminostyryl)- N- methylpyridium (DiA)IBA 12/2021 - 01/2016
2	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 11/2021 - 12/2020
2	Mitotane (Lysodren)FDA Link 10/2021 - 08/2019
2	Transcription Factors (Transcription Factor)IBA 07/2021 - 01/2016
2	LipidsIBA 11/2020 - 01/2020
2	Dehydroepiandrosterone (DHEA)IBA 11/2020 - 01/2017
2	CalciumIBA 06/2020 - 10/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 07/2019
2	18-oxocortisolIBA 01/2019 - 11/2016
2	Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA 01/2017 - 02/2016
2	Oxidoreductases (Dehydrogenase)IBA 01/2016 - 01/2016
1	MineralocorticoidsIBA 06/2022
1	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 06/2022
1	Hydroxysteroid DehydrogenasesIBA 06/2022
1	Bile Acids and Salts (Bile Acids)IBA 06/2022
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 06/2022
1	oxidized low density lipoproteinIBA 01/2022
1	Cholesterol Side-Chain Cleavage Enzyme (CYP11A1)IBA 01/2022
1	Cholesterol Esters (Cholesteryl Esters)IBA 01/2022
1	Amlodipine (Norvasc)FDA LinkGeneric 01/2022
1	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2022
1	somatostatin receptor 2IBA 12/2021
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 12/2021
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 11/2021
1	Tumor Biomarkers (Tumor Markers)IBA 10/2021
1	Sodium-Glucose Transporter 2 InhibitorsIBA 02/2021
1	MelanocortinsIBA 01/2021
1	ElectrolytesIBA 01/2021
1	MethyltransferasesIBA 12/2020
1	O-(6)-methylguanineIBA 12/2020
1	Streptozocin (Streptozotocin)FDA Link 12/2020
1	Parathyroid Hormone (Parathormone)IBA 06/2020
1	Vitamin D FDA LinkGeneric 06/2020
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 05/2020

Therapy/Procedure

9	Adrenalectomy 01/2022 - 09/2017
2	Therapeutics 01/2021 - 08/2019
1	Liver Transplantation 06/2022
1	Lasers (Laser) 01/2022
1	Drug Therapy (Chemotherapy) 10/2021
1	Lung Transplantation 09/2021
1	Kidney Transplantation 01/2021
1	Nephrectomy 08/2020